Biochem/physiol Actions

Primary TargetFootprint studies indicate that spectinomycin exerts regional effects on ribosomal structure

General description

A broad spectrum aminoglycoside antibiotic that contains two glucose moieties. Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure. A resistance gene (aph) which encodes a spectinomycin has been cloned from Legionella pneumophila (disease agent for Legionnaire′s disease) kinase and expressed in E. coli.

A broad spectrum aminoglycoside antibiotic that contains two glucose moieties. Footprint studies indicate that spectinomycin exerts regional effects on ribosomal structure. A resistance gene (aph) which encodes a spectinomycin has been cloned from Legionella pneumophila (disease agent for Legionnaire's disease) kinase and expressed in E. coli. Potency: ≥500 µg/mg.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Thompson, P.R., et al. 1998. J. Biol. Chem. 273, 14788.Noah, J., and Wollenzien, P. 1997. Nucleic Acids Symp. Ser. 36, 178.Suter, T.M., et al. 1997. Antimicrob. Agents Chemother. 41, 1385.Thom, G., and Prescott, C.D. 1997. Bioorg. Med. Chem. 5, 1081.

Packaging

10 g in Glass bottle

Warning

Toxicity: Standard Handling (A)